This study was designed to test the idea that the regulatory regions of human genes have evolved to be resistant to the effects of mutations in their primary function, the control of gene expression.It is proposed that the transcription factor/transcription factor binding site (TF/TFBS) pair having the greatest effect on control of a gene is the on
A mathematical immuno-tumor model proposed by A.Kavaliauskas [Nonlinear Anal.Model.Control 8, 55 (2003)] and consisting of a Cauchy problem for a system of two first-order Toys ordinary differential equations is studied.For some particular parameters values, this model has saddle-node, Hopf and Bogdanov-Takens (BT) singularities.In the case of the
Software defect prediction (SDP) can help developers reasonably allocate limited resources for locating bugs and prioritizing their testing efforts.Existing methods often serialize an Abstract Syntax Tree (AST) obtained from the program source code into Sunglasses a token sequence, which is then inputted into the deep learning model to learn the se
In order to delve into the dynamic evolution process and influencing factors of information sharing decisions among stakeholders under supply chain collaboration, this study constructs an evolutionary game model with suppliers and retailers Toys as the primary entities.Within this model, a combined approach of game theory and prospect theory is emp
Abstract A complete understanding of RNA biology requires methods for tracking transcripts in vivo.Common strategies rely on fluorogenic probes that Tortilla Servers are limited in sensitivity, dynamic range, and depth of interrogation, owing to their need for excitation light and tissue autofluorescence.To overcome these challenges, we report a bi